Author Topic: Lorem Ipsum  (Read 25207 times)

boob_slayer

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Lorem Ipsum
« Last Edit: September 07, 2016, 12:22:47 AM by boob_slayer »

Offline damnips

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Honestly,

I have huge puffy nips, but I do not have any of the other symptoms you have.  I always thought it was a level of estrogen.  And dont worry about wanting to jack it all the time- isnt that how we all reless stress (as well as other things).  haha

Offline turningacorner

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YOU HAVE KLEINFELTERS SYNDROME


mabye?

research it and see what you think.

Offline turningacorner

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you compared the size of your penis to the actors in porn?
intellectually superior?

arghhh

just get surgery man its the conclusion everyone here reaches, if your so smart you will realise this faster than your peers.

Offline Hypo-is-here

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YOU HAVE KLEINFELTERS SYNDROME

mabye?

research it and see what you think.

This is a stupid comment.

First of all you are being sensationalistic in the way you have broached the subject, second of all Klinefelter syndrome is just one form of hypogonadism, with hypogonadism being the bigger more significant issue that can be involved.  Thirdly there are other hormonal imbalances and issues that could be relevant.

Lastly you have no knowledge or experience of these issue something that is patently obvious by the comments you have made and it is best for people to not speak about things that they have no knowledge of.

Klinefelter's syndrome is a genetic disorder and if I know that much all by myself, then it is proven that I don't have klinefelter's because, one of the symptoms of klinefelter's is the inability to comprehend complex things and as I'm intellectually more curious and superior than most of my peers, I can surely negate the idea.

No completely wrong!!

Many men with Klinefelters syndrome have normal and high IQ levels. 

But what gets me on this website is the almost constant reference to Klinefelter Sydrome.  I mean this fascination about Klinefelters Sydrome is ludicrous.  The fact is Klinefelters Syndrome is just one form of hypgogonadism.  There are many forms of hypogonadism that can and do cause gynecomastia.  Likewise there are many other hormonal imbalances that can and do cause gynecomastia.

The fact is every man who has gynecomastia should have an endocrine evaluation by a competent and forward thinking endocrinologist who has an interest in reproductive endocrinology in order to try and uncover the aetiology/acertain the cause of the gynecomastia.

So in short- see such a doctor.

On which note if you need help finding such a doctor in your area let me know and in doing so tell me what city you live in or near and I will try to provide you with relevant contact details.

Offline Hypo-is-here

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Request a copy of all your pathology and accompanying reference ranges.  That way you can review your results in your own good time, keep them for the record and also show them to people who have dealt with hormonal problems or have hormonal problems to get an independent lay persons view.

Offline Hypo-is-here

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I think that the tests had he has indicated cover the issue fairly well.  Just make sure that you get your own copy of the results and reference ranges so that you can review them yourself and get the opinions of others.

The right tests though for the most part, very much so.

Offline Hypo-is-here

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Total Testosterone  418   20 - 49 yrs : 286 - 1510 ng/dL

That is a low normal level.

If you are a young man and have come through puberty that is quite a low level.

I would say that it would be worth having your free testosterone tested to fin out if this is a hypogonadal level.

I say that because a total testosterone value alone without SHBG tested does not provide a diagnosis one way or the other.

Free T3  2.81   3.5 - 5.7 pg/ml


Free T3 is THE crucial free/acting thyroid hormone.

If this lab result is correct and reliable then you have hypothyroidism.

The question is, is whether this is a reliable result or not, certainly though it requires further investigation.

TSH or free T4 mean nothing if the body does not have adequate Free T3.

Hypothyroidism comes with a range of symptoms and you would be best looking into those symptoms to via a credible medical site to see if you fit the profile symptomatically of someone with hypothyroidism.


The bottom line here is that you need to see a decent endocrinologist to further evaluate your situation.

Offline Hypo-is-here

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I visited some medical websites and saw the list of symptoms associated with hypothyroidism. The only symptoms that I had were fatigue, weakness though I don't know myself if the degree of my fatigue is what they would call fatigue. Anyway, all the other symptoms were quite the opposite of what I have. So perhaps, the reports are inaccurate.

Further investigation required, not really sure much more can be said on that note.

I have one other disorder that may perhaps be associated with the endocrine system though I don't know for sure. I have hyperhydrosis. esp. Palmar hyperhydrosis. I heard somewhere that it may be caused due to something wrong in the thyroid gland. I'm not completely sure.

I am not aware of the condition that you have mentioned, so this is a question for your doctor and/or endocrinologist.

Anyway, I'll have to visit the doctor and listen to what he has to say. But, as I expected, the testosterone levels in my body are quite low. I'm 17 y/o now. Will increasing it artificially improve anything?

You need to know if the crucial free testosterone level is low or not, this can be via a reliable free testosterone test or via a guestimate based on total testosterone and SHBG.

You would not want to start replacing testosterone if you do not need it replacing.  Your free testosterone level might be fine.  Then again it might not be, it very much depends on your SHBG level.

If (big if at the moment) you are suffering from low or boarderline low free testosterone then you might wish to consider testosterone replacement with your endocrinologist.  A low free testosterone level and/or a low free T3 level can account for fatigue, so you need these issues evaluated further.

Do you think that, in case I really suffer from hyperthyrodism as you say, there is a connection between it and gyne and also, is there a easy cure to it? <sigh>

I have not said that you have hypothyroidism, I have said if your free T3 level is low and off the bottom of the normal range as that test result indicates then that would point to hypothyroidism due to a lack of the free/active thyroid hormone.  You need another set of thyroid function tests from a competent endocrinologist (along with the free testosterone and or SHBG test).  Any diagnosis would need to be made by an endocrinologist. 

Of note is that I said hypothyroidism, meaning a lack of adequate thyroxin and not hyperthyroidism, which results in too much thyroxin- big difference and two differing conditions with very different symptoms.

There are connections between all the conditions mentioned; low testosterone is an associated condition; 10% of all gynecomastia sufferers have underlying hypogonadism.

Hyperthyroidism, that is too much thyroxin (that is not indicated in your case if your pathology is correct) is an associated condition and an underlying condition in a very small percentage of gynecomastia cases.

And;

Hypothyroidism can indirectly cause gynecomastia by the fact that it promotes increases in adipose fat and this can help promote pseudogynecomastia.

Can you comment on the efficiency of medication in curing gyne where breasts have more of glandular tissue? Would it really work?

Differing medications have been used in controlled studies over the years in treating gynecomastia with differing success rates.

The nature of the studies means that the information has not always been very helpful as those studied were not separately treated with differing medications according to the aetiology of the given cases of gynecomastia.  This means that each given set group of gynecomastia sufferers have tended to be treated with a given medication irrespective of their hormone pathology, or at least not had medication tailored to their given pathology and aetiology of the gynecomastia.

So we have seen dihydrotestosterone, Tamoxifen, Clomiphene, testosterone, Danazol studies etc.

Each has had differing success rates, but the numbers mean little.

For example if the cause of the gynecomastia is excess estradiol then an anti estrogen or a newer aromatase inhibitor is most likely going to provide a greater chance of reduction or resolution of gynecomastia.  But in a man with elevated SHBG Danazol is more likely to offer hope, whereas a man with a low testosterone level and consequently low dihydrotestosterone might see a greater reduction in gynecomastia via dihydrotestosterone. 

I could fish out numbers from controlled studies if you wish (let me know if you want that), but in all honesty it is a little irrelevant because it depends on what the underlying cause of the gynecomastia is. 

The big problem with medications in the US are two fold.

1 You are unlikely to be offered any medication to help you get rid of the gynecomastia in the US.  Testosterone will only be given out if you are hypogonadal to treat the hypogondism and it may help or make make the gynecomastia worse (differs person to person based on dosage and response).  If you have hypothyroidism it may or may not help.  The medications that would help will probably not be prescribed (they tend to be used more in Europe).

2 If you have had gynecomastia more than a year and a half it will have become fibrous and not/less responsive to endocrine altering medications.

------------------------------------------------------------------------------------------------

All this is jumping too far ahead in any case.  You need to see an endocrinologist to further evaluate your situation.

If you need help in trying to find an endocrinologist in your area I might be able to help if you tell me the nearest city to where you live. 
« Last Edit: October 18, 2007, 11:00:36 PM by Hypo-is-here »

Offline problem man

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just one small question hypo, my SHBG is less than 2 (normal range 13-71) but both free and total Testosterone is higher than normal range(i have a high libido). my endo said no problem, what do u think hypo? can the low shbg cause boob regrowth?
thanks.
« Last Edit: October 19, 2007, 03:13:28 AM by problem man »

Offline Hypo-is-here

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just one small question hypo, my SHBG is less than 2 (normal range 13-71) but both free and total Testosterone is higher than normal range(i have a high libido). my endo said no problem, what do u think hypo? can the low shbg cause boob regrowth?
thanks.

Your endocrinologist should not just sign off such a strange hormonal reading as "no problem" without further investigation.

Low SHBG, particularly VERY low SHBG can result in elevated free testosterone values and occasionally overtly high free testosterone levels.  Now SHBG or sex hormone binding globulin, to give it its full title not only alters the crucial level of free testosterone it also crucially alters the free level of estradiol.  This is something a lot of endocrinologists unfortunately pay little attention to.  SHBG might bind to testosterone with greater affinity than estradiol, but it does nevertheless have an important role in binding to estradiol.

What does this mean then in practical terms for a man with low or very low SHBG?

It means that a seemingly normal serum estradiol level might actually be too high a level of estradiol given the modifying factor of SHBG.  It means that a given individual might have to have a low normal estradiol level in order to avoid high free estradiol and the problems inherent with elevated estradiol; namely hot flushes, gynecomastia, reduced libido, erectile dysfunction, reduced or lack of morning erections and increased adipose fat around the hips and waist.

Some laboratories can perform free estradiol tests and I think that a free estradiol test would be warranted in a man with a history of gynecomastia and a very low SHBG level.

If you do not have symptoms associated with high estradiol then your free estradiol level is highly unlikely to be a problem, certainly a high libido, good erections no problem with hot flushing and excess sweating etc would be counter indications of any problem.

Low SHBG can be caused by differing underlying condition such as hypothyroidism and hormonal imbalances, it can be caused by hypothyroidism, by excess cortisol or prolactin production etc.  It can be caused by anabolic steroid abuse or by certain medications.  Your endocrinologist should be ruling such things out and not just dismissing the result.

It is possible that you will not learn what the cause of the low SHBG is, but it should be investigated nevertheless. 

If you are well in yourself and you do not suffer from the symptoms of excess estradiol, hypothyroidism, high cortisol etc, if you are well and feel healthy then one would hope that the gynecomastia will not return.       







 

Offline Hypo-is-here

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It means that the breast tissue is dense enough to be seen via ultrasound.  It means that you do have breast tissue that would "probably" require surgical removal if you want rid of it (probably).

That means surgery would need to involve glandular excision and not just liposuction.

That is my laymans impression, obviously you need to await the other results and see what happens and what is suggested by your endoc and by a surgeon perhaps.

Offline itsgoingdown

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Hey,

Training bodybuilding myself, I dont think the fat under your abs has alot to do with your hormonal levels (I'm not a doctor!).

Needless to mention I havent seen you but I would say you've had either a slight or even pretty good amount of fat between ages 12 to min 15 resulting in both gynecomastia and your condition now.

The fat under the abs usually burn as the last amount of fat in the entire body and therefore in order to get a flat or even a "six-pack" you need to train hard and keep a good diet.

Do check your self out to be on the safe side but I wont really worry about stuff I dont know about and would instead go to the gym and work just a bit harder  ;)

Good luck.

 


Offline itsgoingdown

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I asked my doctor ones if tamoxofin is worth a try but he said taking this medicine is dangerous and it might lead to bad long term side effects such as disfunction in the pennis!!! This is what I will never go towards for any reason.

This is my information according to 3 different doctors (1 endo, 2 general) but do wait for other suggestions before you take the medicines.

Good luck.

Offline Hypo-is-here

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Hey Hypo,

I visited my doctor today. He reviewed the lab reports and said that he didn't actually need the reports to confirm that I had pubertal gynecomastia.

That makes no sense whatsoever; of course he required the lab reports to ascertain the nature of the gynecomastia.  To suggest otherwise would be like saying that if a major disorder was found that the cause would still be pubertal in origin- which of course it wouldn’t be.

He just needed them to make sure that I didn't have any major disorders.

Exactly, to see if there was an underlying causative disorder- he has contradicted himself.

I told him about you suggesting the necessity for testing of free testosterone. But, he said that it is not essential because my testicles were 15ml and that was a sign that I was doing fine. He just said that his clinical evaluation negated any doubts relating free testosterone levels.

But he never tested SHBG, which would negate the size of the testicles as any issue relating to elevated SHBG would mean testosterone production would be high enough but free testosterone to lower due to testosterone being bound in the blood.

There is no excuse for not testing free testosterone where SHBG has not been tested and he is talking complete rubbish.

I am not saying you have a problem at all, but I am saying that your testosterone is nearer the low end of normal for a young man and that without viewing free testosterone or ascertaining a likely free testosterone by calculated testosterone (CT) via an equation involving total testosterone and SHBG, without which that you cannot accurately evaluate androgen status.  He has failed to accurately evaluate your androgen status.

Furthermore why has your low level of thyroxin/free T3 not been further investigated?

Result 2.81   3.5 - 5.7 pg/ml

Quite poor in my view particularly given the symptoms you have reported in conjunction with the gynecomastia.




He explained that puberty in men happens over a long period and that I already have a chance of it going away but anyways, he subscribed the following medication to help the process:-

tab. tamoxifen 20mg

So lets get this straight he has not fully evaluated your androgen status, he has ignored the lack of thyroxin and not further investigated the potential thyroid issue and then he has prescribed Tamoxifen which loweres estradiol when you have a low estradiol level as evidenced by your pathology (LESS THAN 20   upto 56 pg/ml) ?
 
This is a bit of a joke to be honest.  He has given you the most inappropriate treatment I can think of given your situation.

once in the night after dinner for about 3-6 months and see if it subsides. He explained that this wouldn't have any side-effects because it is usually subscribed for women with breast cancer to reduce their estrogen or something. So, it will help just as good for men with breasts. He also told me that it wouldn't have any side-effects.

Is he right? Is there a hard evidence against his suggestion that tamoxifen is safe and wouldn't feminize my features further? Can I go ahead and try the medication?

Oh no it wont cause feminization at all.  What it will almost certainly do at that dose and duration is completely decimate an already low estradiol level.

That will mean that your gynecomastia might well decrease, but I would also expect you to start getting hot flushes and sweats at night at that dose, I would expect you to start getting back and joint pain quite badly, I would expect you to lose the ability to achieve or maintain and erection, for you to be left with a low libido and generally feel awful and fatigued/exhausted.  You might also adversely affect your thyroid function further a symptom of which would be a sore throat.  In the short term you might feel very well, but I simply cannot see you not suffering once you are past a couple of weeks.

The gynecomastia might be reduced, particularly if it has been present for less than a years and a half and still in the early phase, but seriously there is so much wrong here to my mind.  Any major improvement in the gynecomastia would be expected within about 6-8 weeks.

You might wish to go ahead with the prescription, if you do watch out for the symptoms I have spoken about developing after a somewhat short time frame.

P.S

If I were you I would want a second opinion which at least looked at your free testosterone and SHBG as well as your thyroid status.  If everything turns out ok, for whatever reason, lab error of the prior free T3 result for example then I would be looking to surgery given that elevated estradiol is unequivically not the issue and anti estrogen treatment inappropriate.  Myself I still think there could be an androgen or thyroid issue here, partiuclarly given that low free t3 result.   



« Last Edit: October 31, 2007, 03:28:29 PM by Hypo-is-here »


 

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