Reversing SSRI's effects?

[legtfogyno]

I'm 15 with a 21 BMI. I've been taking SSRIs since I was 8. I recently quit prozac. Within 5 days my gyno had reduced by a noticeable amount. Best time of my life. Now my doctor prescribed me Luvox (Fluvoxamine) and it has come back but this time very irritated. I cannot find why SSRIs cause gyno anywhere on the internet. There are assumptions, but no proof. Liver failure, increased estrogen, and increased estrogen sensitivity are possibilities. I've tried ZMA (all natural supplement containing zinc, magnesium, estrogen inhibitors) and it seemed to help a bit and up my libido but it caused me bad acne so I only take it once the last batches acne clears up. Anyways the SSRIs that ive been taking have been causing it and it is reversible but I can't stop taking my ssri because of my depression (ironic because gyno is making me depressed and the ssri is causing the gyno) so how do I get rid of it? Can't increase testosterone because that increases estrogen alongside with it, so I need an anti Estrogen. What do you guys recommend for a supplement, over the counter, preferably natural with no side effects. 

[xelnaga13]

Research serotonin, dopamine, and prolactin for your answer. Basically more serotonin (ssri effect) equals less dopamine and less dopamine equals higher prolactin. Higher prolactin combines with estrogen and igf1 to cause gyne.

More supplementation is not advisable. Treating hormonal disturbances caused by medication with more medication will only result in more complex side effects. 

[legtfogyno]

I forget to mention that I used to take 40mg of vyvanse alongside with prozac. When I was prescribed my luvox last sunday, I was also switched to 60mg of adderall. Stimulants drastically increase dopamine, from what I've read.

[xelnaga13]

Stimulants do increase dopamine release.

The problem is that all those neurotransmitters effect the pituitary gland and the pituitary gland controls your sex hormones.

With everything you have on board it would be impossible to navigate a solution.

[legtfogyno]

I'm going to get off luvox and all SSRIs for good over the summer but during school I dont want the withdrawal symptoms. Just seeing if theres a medicine wiz out there that can recommend a estrogen inhibitor or something

[twoshirts]

I got gyno around age 14.  I am sorry you are on so many different prescriptions.  If I lived near you I would say drop the drugs, let's go fishing!  Hope it all works out for you kid.  Life is a fun ride, ride it hard!

[xelnaga13]

I'm going to get off luvox and all SSRIs for good over the summer but during school I dont want the withdrawal symptoms. Just seeing if theres a medicine wiz out there that can recommend a estrogen inhibitor or something

@ Op- There's a laundry list of anti estrogen and estrogen blocking medications. What Im trying to convey is that as long as you are being treated for your mental health, gyne is priority number two. Estrogen is not your enemy. It's responsible for the proper production and absorption of neurotransmitters.

Essentially we are discussing contradictory treatment plans. This is a topic that should be brought to the attention of your primary care doctor and specialists.

[legtfogyno]

I know the root of the problem (prozac/luvox) I just need the tools to cut off the damn limbs if you know what I mean. I'm curious as to what the SSRIs do to cause gyno? Is it liver function?

[xelnaga13]

I know the root of the problem (prozac/luvox) I just need the tools to cut off the damn limbs if you know what I mean. I'm curious as to what the SSRIs do to cause gyno? Is it liver function?

It's not liver function. The only way that the liver would cause gyne would be if it was damaged and unable to preform the simple task of clearing excess hormones. SSRI are not liver toxic enough to cause that kind of damage, even in extreme cases of abuse. Tylenol is more toxic.

ASSUMING for a moment that it is in fact the ssri's causing your gyne. My hypothesis would be as follows. SSRI's raise serotonin levels. Higher serotonin levels equal lower dopamine levels, because they counter-balance each other. Okay- So now it gets a little tricky. Your pituitary gland has several different types of dopamine receptors. When those receptors are activated it tells the gland to stop producing prolactin. When the receptors are unoccupied it signals the gland to produce more prolactin. Now prolactin can go about its business. It not only directly stimulates breast developement ( same hormone in pregnant women) but it also has the ability to lower male hormones levels significantly.

Now your body finds its self in the perfect storm of gyne. High prolactin, low testosterone, and estrogen combine forces to produce gyne. It's a specially feisty version of gyne that's typically aggressive, fast developing, and untreatable even when hormone levels are rectified.   

[TheTimeIsNigh]

I'm pretty sure there isn't a causal link b/t luvox and gyno.. Another SSRI that may be worth looking into is Lexapro.. I believe both of those are a safe bet when it comes to gyno/prolactin/estrogen..