If someone wants to hunt back through my posts under the name hypo;
About a year ago I brought to the attention of the board a detailed medical document that explained the affects of marijuana on the endocrine system of almost every conceivable animal.
In all the studies of which there were many, marijuana had an adverse impact on the androgen to estrogen ration of the animals concerned.
There was not one animal studied where this was not so.
Whilst not being a human trial (something that would bee deemed inappropriate), it is a good indicator as to what probably happens in the human endocrine system.
To wit the argument goes that everyone knows one person or another who smokes a lot of marijuana and yet they are not affected.
My thinking on this is that some people have healthier endocrine systems than others.
If an individual has a high natural testosterone level and a low estrogen level, then they might not be affected to any noticeable degree at all, but if an individual has a propensity for gynecomastia having a low or low normal testosterone and or an estrogen level that is not particularly low then the impact of marijuana could be far more significant.
All of the human statistical information relating to marijuana is that, gynecomatia is seen in a higher than expected proportion of people who smoke it.
It would seem there is a weak but positive association between the two, hence the question often being asked by endocrinologists and plastic surgeons.
All this said the link is not nearly as strong as it is with other substances such as steroid abuse which accounts for 25% of all gynecomastia sufferers or as is seen with associated conditions such as hypogonadism which accounts for 10% of all gynecomastia sufferers and liver problems which account for 8% of all sufferers.